... composite Egyptian legend the narrative would be more intelligible. The mandrake is such a sedative as might have been employed to calm the murderous frenzy of a maniacal woman. In fact it is closely allied to hyoscyamus, whose active principle, hyoscin, is used in modern medicine precisely for such purposes. I venture to suggest that a folk-tale describing the effect of opium or some other "drowsy syrup" has been absorbed into the legend of the Destruction of Mankind, ... — The Evolution of the Dragon • G. Elliot Smith